Wolfgang Mieder "Proverbs: A Handbook"
Greenwood Publishing Group (June 2004) | ISBN 0313326983 | 328 Pages | PDF | 2.6 Mb
Just about everyone has heard at least one proverb, and most people have heard more. Proverbs offer a concise record of folk wisdom and have appeared in oral tradition, literature, art, and popular culture for centuries. One of the most varied and fascinating types of folklore, proverbs are studied at all levels and are of interest to a wide range of audiences. Written by the foremost authority on proverbs, this reference gives high school students, undergraduates, and general readers a concise yet comprehensive overview of proverbs in world culture. The volume begins with definitions and classifications of proverbs and a discussion of their origin and dissemination. It then discusses several representative proverbs from around the world. This is followed by a review of scholarship on proverbs. The book next looks at how several proverbs have appeared in political speeches, literature, popular culture, and everyday life. The handbook closes with a bibliography of print and electronic resources and a glossary. Included are numerous photos illustrating the role of proverbs around the world.
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Proverbs: A Handbook
New Drug Development: Design, Methodology, and Analysis
J. Rick Turne, "New Drug Development: Design, Methodology, and Analysis "
John Wiley & Sons, Inc.; 1 edition (2007) | ISBN: 047007373X | 270 pages | PDF | 13,4 Mb
This book acquaints students and practitioners in the related fields of pharmaceutical sciences, clinical trials, and evidence-based medicine with the necessary study design concepts and statistical practices to allow them to understand how drug developers plan and evaluate their drug development. Two goals of the book are to make the material accessible to readers with minimal background in research and to be straightforward enough for self-taught purposes. By bringing the topic from the early discovery phase to clinical trials and medical practice, the book provides an indispensable overview of an otherwise confusing and fragmented set of topics. The author’s experience as a respected scientist, teacher of statistics, and one who has worked in the clinical trials arena makes him well suited to write such a treatise.
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Medical | Handbook of Pain Relief in Older Adults
Handbook of Pain Relief in Older Adults (Aging Medicine) by Michael Gloth
Humana Press | ISBN: 1588292177 | 288 pages | 2003-12-1 | PDF | 3.6 MB
A comprehensive assessment of the clinical, psychological, legal, and cultural aspects of dealing with unnecessary pain in the elderly. The authors explore pharmacotherapy (nonopioids, opioids, and adjuvants), interventional strategies, the role of rehabilitation in managing pain in seniors, and the problems of pain management in long-term care. Supplementary features include continuing medical education (CME) certification, a CME posttest and evaluation to be completed and submitted for credit, and an appendix of analgesics that details starting oral doses, maximum daily oral doses, and special considerations for the elderly. 6.5 AMA/PRA category 1 CME credits with completion of included test.
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Medical | Diagnostic Criteria in Neurology
Diagnostic Criteria in Neurology (Current Clinical Neurology) by Alan Lerner
Humana Press | ISBN: 158829482X | 240 pages | 2006-04-01| PDF | 1.5 MB
A compendium of the latest published diagnostic criteria for a diverse group of neurological conditions. The criteria cover a wide spectrum of neurological conditions whose diagnosis does not depend solely on histopathology (e.g., brain tumors), including cerebrovascular diseases, dementias and behavioral disorders, demyelinating disorders, and disorders of consciousness and brain death. Standardized criteria are also provided for epilepsy, genetic syndromes, headache, immune-based disorders, infectious diseases, movement disorders, neuromuscular disorders, and sleep disorders. A dazzling array of tables summarizes useful information on both common and uncommon neurological conditions, including many genetic and pediatric neurological disorders. Innovative and authoritative, Diagnostic Criteria in Neurology begins to do for neurology what the DSM (Diagnostic and Statistical Manual) did for psychiatry.
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Medical | Male Hypogonadism (Contemporary Endocrinology)
Male Hypogonadism (Contemporary Endocrinology) by Stephen Winters
Humana Press | ISBN: 1588291316 | 408 pages | 2003-12-12 | PDF | 4.1 MB
This lucid interpretation of the latest scientific information on male reproductive endocrinology provides a thorough understanding of the pathophysiology, clinical characteristics, and treatments for disorders that adversely affect testicular function. The authors focus on the specific causes of gonadotropin deficiency and testicular failure arising from disorders of the brain and the testis and from gene defects and chronic illness. Additional chapters describe the endocrine mechanism for the decline of testicular function with aging, summarize the data supporting the negative impact of environmental toxins on testicular function, and discuss the testicular consequences of exercise and obesity.
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Medical | Hypertension and Hormone Mechanisms
Hypertension and Hormone Mechanisms by Robert Carey
Humana Press | ISBN: 1588294080 | 378 pages | 2007-09-14 | PDF | 4 MB
Hypertension and Hormone Mechanisms reviews novel developments in the endocrinology of hypertension with emphasis on new discovery during the past five years and perspectives on the future. Written by authors who have spearheaded recent advances, chapters cover innovations in our understanding of the reninangiotensin-aldosterone, the sympathoadrenal, and the renal dopaminergic systems. World-renowed researchers also discuss natriuretic peptides, vasoactive substances and vasopeptidases, insulin, free fatty acids, and the insulin resistance syndrome, sex hormones, and the vasculature and selected areas of diagnosis and therapy.
With a focus on new developments in hormones and autacoids related to hypertension, Hypertension and Hormone Mechanisms provides a resource that will lead to new, active research in the fundamental mechanisms of hypertension.
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Medical | Genomic Disorders: The Genomic Basis of Disease
Genomic Disorders: The Genomic Basis of Disease by James Lupski
Humana Press | ISBN: 1588295591 | 448 pages | 2006-04-15 | PDF | 3.8 MB
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
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Medical | The Handbook of Contraception: A Guide for Practical Management
The Handbook of Contraception: A Guide for Practical Management (Current Clinical Practice) by Donna Shoupe
Humana Press | ISBN: 15882959906 | 312 pages | 2006-08-11 | PDF | 1.8 MB
The Handbook of Contraception: A Guide for Practical Management provides a comprehensive review of contraception methods for all reproductive-aged women, including those who are young and healthy, postpartum, perimenopausal, adolescent, or who have a medical disease. Because of the vast and diverse list of various contraceptive methods available, this text updates the health care provider with information on safety, practical counseling tools, advantages, and disadvantages of each contraception method. This superb reference offers inclusive information on oral, injectable, emergency, and various cervical barrier contraceptives, as well as behavioral methods of contraception and sterilization methods. An extensive review of currently available laparoscopic and hysterscopic tubal sterilization techniques is also included as well as a chapter introducing the new surgical contraceptive implant, Implanon®.
The Handbook of Contraception: A Guide for Practical Management is designed to give the modern health care provider up-to-date information on safety, side effects, advantages, and practical counseling tools.
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Medical | Cardiovascular Molecular Imaging
Cardiovascular Molecular Imaging by Robert Gropler
Informa Healthcare | ISBN: 0849333776 | 368 pages | 2007-07-23 | PDF | 11.7 MB
Based on a groundbreaking NIH symposium sponsored by the American Society of Nuclear Cardiology, this source will stand as the first all-inclusive guide to the targeted molecular imaging of the cardiovascular system. With color throughout, and packaged with a user-friendly CD-ROM, this source will cover new methods for the analysis and management of cardiovascular pathophysiological processes and probe new technologies to analyze cardiovascular receptors, reporter probes and gene expression, vascular structures, and biological processes that affect the heart and associated vessels.
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Cardiovascular Biomarkers: Pathophysiology and Disease Management
Cardiovascular Biomarkers: Pathophysiology and Disease Management by David Morrow
Humana Press | ISBN: 1588295265 | 640 pages | 2006-05-05 | PDF | 5.7 MB
Internationally recognized opinion makers and experts in clinical and laboratory medicine synthesize the latest developments in the use of cardiac biomarkers by the practicing physician. The authors focus on integrating biomarkers into the contemporary clinical management of patients with cardiovascular disease, emphasizing clinical studies, evidence-based diagnostic algorithms, and critical pathways for triage and therapy, whenever available. They also illuminate the connections between specific biomarkers and the basic pathophysiology of cardiovascular disease, explain the analytical properties of the assays relevant to clinical practice, and highlight emerging novel biomarkers and new direction for biomarker development. Numerous figures, illustrations, and tables make key evidence and practical guidelines easily accessible. The book makes clear as never before to today's busy cardiologists, emergency room physicians, and internists how the various assays perform, which ones they should order to evaluate their patients, and how they might change their therapeutic approach based on the results of a biomarker assay.
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Medical | Management of Benign Prostatic Hypertrophy
Management of Benign Prostatic Hypertrophy by Kevin McVary
Humana Press | ISBN: 1588291553 | 280 pages | 2003-11-25 | PDF | 4.4 MB
A concise, up-to-date review of the many new therapies available for the treatment of benign prostatic hypertrophy (BPH). The authors concisely evaluate the latest minimally invasive therapies, as well as time-tested surgical treatments, and review the medical therapies for BPH, namely a-adrenergic antagonists, 5-a reductase inhibitors, and their therapeutic combinations. Additional chapters examine the pathophysiology and natural history of BPH, its epidemiology, and the urodynamic evaluation of lower urinary tract symptoms. A perfect reference source for the practicing urologist seeking sound guidance on the best approach to his patients.
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Medical | Bone Densitometry in Clinical Practice: Application and Interpretation
Bone Densitometry in Clinical Practice: Application and Interpretation (Current Clinical Practice) by Sydney Bonnick
Humana Press | ISBN: 1588292754 | 436 pages | 2003-09-17| PDF | 4.3 MB
This fully updated and dramatically expanded edition will allow family physicians and specialists to fully understand not only what they need to do, but also why. New to this edition-over half the book-are discussions of the clinical guidelines for selecting patients for densitometry measurements, various questionnaires and indices that have been developed to help patients identify themselves as candidates for bone mass measurements, and specific densitometry applications of diagnosis, fracture risk prediction, and monitoring changes in bone density. Updated material includes an expanded review of the effects of diseases and drugs on bone density, new standardization formulas for the hip subregions and forearm, statistical devices necessary to "test the test," and guidance on how to do a short-term precision study and apply the result to clinical practice. An accompanying CD-ROM contains a Precision Calculator, a Statistical Confidence Calculator for Measured Change in BMD, OST Nomograms, a Patient Risk Factor Questionnaire, and a CME review, which, if successfully completed, can lead to 30 hours of AMA Category I continuing education credit
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Medical | The Art and Science of Cardiac Physical Examination (Contemporary Cardiology)
The Art and Science of Cardiac Physical Examination (Contemporary Cardiology) by Narasimhan Ranganathan
Humana Press | ISBN: 1588297764 | 432 pages | 2006-09-15 | PDF | 3 MB
A panel of academic clinicians brings the art and science of the clinical cardiac examination to the bedside with a tour de force tutorial on the techniques needed to elicit various physical signs and to interpret them in relation to the patient's symptoms and underlying cardiac condition. Drawing on twenty-five years of teaching and training physicians and physicians-to-be, the authors integrate the physiology, pathophysiology, and mechanisms behind the various physical signs with a thorough and easy-to-use practical approach that makes physician feel more comfortable and competent performing the cardiac physical examination. The authors pay particular attention to the interpretation of the jugular venous pulsations and contour and make the physiology and pathophysiology of the normal and abnormal arterial pulse interesting and relevant. A unique and original companion video CD presents close to 140 clinical examples taken from actual patients, complete with audio recordings of various heart sounds and murmurs displayed in real time as seen on an oscilloscope. Additional video recordings show both precordial pulsations and jugular pulsations from patients with a variety of cardiac lesions, and illustrate certain unusual clinical conditions through simultaneous echocardiographic images and recordings of heart sounds and murmurs.
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Medical | Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)
Steven A. Frank , "Dynamics of Cancer: Incidence, Inheritance, and Evolution (Princeton Series in Evolutionary Biology)"
Publisher: Princeton University Press | ISBN: 0691133662 | 400 Pages | PDF | 2.8 Mb
The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset.
The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer.
This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.
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Medical | Directory of Therapeutic Enzymes
Directory of Therapeutic Enzymes
CRC Press | ISBN: 0849327148 | 2005-08-12 | PDF | 312 pages | 9.75 Mb | RS
Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product. Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications. The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.
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Medical | Antiemetic Therapy (US$143.50)
Antiemetic Therapy (US$143.50)
Stationary Office | Pages:234 | 2003-05 | ISBN / ASIN:3805575475 | 3 MB
Book Description:
Prevention and treatment of nausea and emesis are very important issues for the patient’s well-being under different clinical as well as outpatient situations. This multidisciplinary book on this topic should bridge the gap between basic research and clinical practice, and we hope that many scientists will be able to benefit from it. In this context I am very grateful to everybody who was involved in the preparation and completion of this book.
Various and partly still unresolved pathomechanisms play roles in nausea and emesis in humans, and appropriate animal models are not always available for preclinical research on antiemetic drugs. Therefore, only the results from studies in the clinical setting can decide a new compound’s utility. Basically, we have a rather small number of drugs in the established treatment regimens, however some new interesting compounds are being studied in clinical trials.
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A Computer Scientist's Guide to Cell Biology
A Computer Scientist's Guide to Cell Biology
Publisher: Springer-Verlag | Author(s): William W. Cohen | ISBN: 038748275X | Release Date: 25 June 2007 | Size: 4.9 MB | PDF | Pages: 100
This practical guide provides a succinct treatment of the general concepts of cell biology, furnishing the computer scientist with the tools necessary to read and understand current literature in the field.
The book explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. After a brief introduction to cell biology, the text focuses on the principles behind the most-widely used experimental procedures and mechanisms, relating them to well-understood concepts in computer science.
The presentation of the material has been prepared for the reader’s quick grasp of the topic: comments on nomenclature and background notes can be ascertained at a glance, and essential vocabulary is boldfaced throughout the text for easy identification.
Computer science researchers, professionals and computer science students will find this an incomparable resource and an excellent starting point for a more comprehensive examination of cell biology.
"This concise book is an excellent introduction for computer scientists to the exciting revolution under way in molecular biology. It provides lucid, high-level descriptions of the fundamental molecular mechanisms of life, and discusses the computational principles involved. I wish this little gem was available when I was ‘learning the ropes’– it would have been my first choice of reading material."
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Methods in Molecular Biology Volume 201-300
Protein Nanotechnology: Protocols, Instrumentation, and Applications(Methods in Molecular Biology Volume 300
Humana Press | 1588293106 | Edition - February 1, 2005 | PDF | 480 pages | 13.4 MB | 646 MB
Leading experts in nanobiotechnology comprehensively review the most recent advances in instrumentation and methodology, as well as their applications in genomics and proteomics. The authors provide a wide variety of techniques and methods for dealing with protein functions and structures at the nanoscale level, including nanostructured systems, nanomaterials, carbon nanotubes and nanowires, optical nanosensors, and nanoelectrodes. Among the highlights are techniques for the in vivo tracking of biochemical processes using fluorescent molecular probes and nanosensors, and the exploration of biochemical processes and submicroscopic structures of living cells at unprecedented resolutions using near-field optics. Also discussed is the development of nanocarrier methodology for the targeted delivery of drugs whose shells are conjugated with antibodies for targeting specific antigens.
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Surgical Management of Congestive Heart Failure (Contemporary Cardiology)
"Surgical Management of Congestive Heart Failure (Contemporary Cardiology)"
Publisher:Humana Press | Pages:344 | 2004-10-15 | ISBN:1588290344 | PDF | 3.57 MB
James C. Fang, MD, and Gregory S. Couper, MD, have assembled a panel of prominent surgeons and cardiologists to review the latest clinical, scientific, and investigational surgical and mechanical approaches to heart failure in hopes of improving the lives of this challenging group of patients. Topics range from such traditional strategies as high-risk surgical revascularization in advanced coronary artery disease, to more novel approaches such as ventricular reconstruction and mechanical assist devices. Many chapters are contributed by the original pioneers of specific surgical techniques, which provide s invaluable perspective from personal experience.
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